Tuesday, 16 August 2011

Causes Of Cancer

Cancer is caused by changes (mutations) in DNA in cells. The DNA of a cell contains a set of instructions that tells the cell how to grow and divide. Errors in the instructions, may allow a cell to become cancerous.

What gene mutations not?

A mutation can charge a healthy cell to:

Enable rapid growth. A mutation can cause an oncogene, a gene that tells a cell to grow and divide rapidly. This creates many new cells, all with the same oncogene mutation that allows them to grow and divide as fast as normal.

They can not stop the uncontrolled growth of cells. Cells contain genes known as tumor pathogenesis, which recognize an out-of-control growth and to act to stop it. But if the mutation occurs in a tumor suppressor gene, the gene can be reduced or can be turned off completely. This allows the mutated cells to continue to grow and divide.

Mistakes in the DNA repair defects. DNA repair genes to identify and correct DNA mutations. Mutations in the DNA repair gene means that the gene may have no errors in the DNA. This allows more DNA mutations occur.

Mutations in oncogenes, tumor and pathogenesis of the DNA repair genes are the most common cancer found. But many other genetic mutations may contribute to cancer.

What causes mutations?

Sometimes you are born with a genetic mutation. Or a gene mutation can be caused by forces within your body, such as hormones, viruses and chronic inflammation. Genetic mutations can also be caused by forces outside their body, such as ultraviolet (UV), chemicals that cause cancer (carcinogens) or radiation.

How can genetic changes interact with each other?

Scientists believe that more than one genetic mutation, it is necessary to cause cancer. It is not clear how many mutations are collected in cancer formation. And 'likely that this varies in different types of cancer.

Mutations in the gene, you are born with and those you have your whole life to work together to cause cancer. For example, if you have inherited a genetic mutation that predisposes to cancer does not mean that you are sure to have cancer. Instead you can use one or more other mutations that cause cancer. Your inherited genetic mutation may make you more likely than others to develop cancer when exposed to a carcinogen. The genetic mutation begins the process of cancer, the carcinogen may play a role in cancer development.

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